Florastor Sachet – Complete Product Description for EZ Chemist Online Pharmacy

Florastor Sachet contains Saccharomyces boulardii lyo, a probiotic yeast used to restore gut flora, prevent and treat antibiotic-associated diarrhea, traveler’s diarrhea, and Clostridium difficile infections. It helps balance intestinal microflora and supports gastrointestinal health. Clinically proven, Florastor is safe for children and adults and does not require refrigeration.

Product Name:
Florastor Sachet

Active Ingredient:
Saccharomyces boulardii lyo (freeze-dried live yeast cells)

Other Common or Brand Names:
Generic: Saccharomyces boulardii

Brand Variants:

Florastor

BioFlor

Ultra-Levure

SB Floractiv

Enterol (Europe)

Drug Classification:
Therapeutic Class: Probiotic / Antidiarrheal agent

Pharmacologic Class: Live yeast-based biotherapeutic agent

Regulatory Status: Over-the-counter (OTC) dietary supplement in many countries, sometimes classified as prescription in severe gastrointestinal disorders.

Mode of Action:
Saccharomyces boulardii works by restoring and maintaining the natural flora of the gut. It functions through:

Inhibiting pathogenic bacteria by blocking toxin receptors and competing for nutrients

Enhancing intestinal barrier function

Modulating immune response and reducing inflammation

Producing proteases that neutralize toxins such as Clostridium difficile toxin A and B

Maintaining pH and suppressing pathogen adhesion

Clinical studies (McFarland, 2010, Therapeutic Advances in Gastroenterology) support its efficacy in preventing antibiotic-associated diarrhea and Clostridium difficile recurrence.

Indications and Clinical Uses:
Florastor Sachet is indicated for the prevention and treatment of:

Antibiotic-associated diarrhea (AAD)

Clostridium difficile infections (CDI) and prevention of relapse

Acute infectious diarrhea

Traveler’s diarrhea

Diarrhea in tube-fed patients

Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) as an adjunct

Restoration of normal gut flora post-infection or medication use

Dosage and Administration:
Adults and Children ≥2 Years:

1 sachet (250 mg) once or twice daily

In severe cases (e.g., during antibiotics or active diarrhea): up to 500 mg twice daily

Take with food or liquid (not hot or carbonated)

Infants (<2 years):

Consult a pediatrician

Typically 1 sachet daily, mixed with formula or soft food

Duration:

5–10 days for acute diarrhea

Up to 30 days for antibiotic-associated use or prevention

Florastor is stable at room temperature and does not require refrigeration.

Prescribing and Usage Guidelines:
Can be taken concurrently with antibiotics (unlike many bacterial probiotics)

Should not be mixed with hot beverages or alcohol

Safe for long-term use under medical advice

Safety Information:
Side Effects:
Common:

Mild bloating or gas

Constipation (uncommon)

Serious (Rare):

Fungemia (in severely immunocompromised or ICU patients)

Allergic reactions (especially in patients with yeast allergy)

A study in Clinical Infectious Diseases (2014) reported rare cases of fungemia in ICU patients receiving probiotics intravenously or via central lines.

Warnings and Precautions:
Do not administer via central venous catheters

Not recommended for severely immunocompromised patients, including those undergoing chemotherapy or with HIV/AIDS, unless under close supervision

Use with caution in patients with yeast allergies

Monitor for signs of systemic infection in high-risk populations

Drug Interactions:
Antifungal medications (e.g., fluconazole, ketoconazole): Reduce the efficacy of Saccharomyces boulardii

No interaction with antibiotics – can be co-administered safely

Safe with most common medications unless antifungal agents are used

Pregnancy and Lactation:
Generally considered safe during pregnancy and breastfeeding

Clinical data limited; use under medical advice in pregnant women

Storage Instructions:
Store at room temperature (15–30°C)

No refrigeration required

Protect from excessive humidity and light

Keep sachets in the original packaging until use

Frequently Asked Questions (FAQs)
Q1: What is Florastor Sachet used for?
A1: Florastor is used to prevent or treat diarrhea caused by antibiotics, infections, or travel, and to support healthy gut microbiota.

Q2: Can I take Florastor with antibiotics?
A2: Yes, Florastor can be safely taken with antibiotics because it is a yeast-based probiotic and is not affected by antibacterial agents.

Q3: Is Florastor safe for children?
A3: Yes, Florastor is safe for children over 2 years and even infants under medical advice.

Q4: How should I take Florastor Sachet?
A4: Mix the contents of the sachet with food, juice, or water. Do not mix with hot or carbonated drinks.

Q5: Does Florastor need refrigeration?
A5: No, Florastor is shelf-stable and does not require refrigeration, making it ideal for travel.