Florastor 250mg – Saccharomyces boulardii Probiotic Capsules for Diarrhea, Antibiotic-Associated Gut Health & IBS – Buy Online at EZ Chemist

Florastor is a probiotic supplement containing Saccharomyces boulardii CNCM I-745, a beneficial yeast used to prevent and treat antibiotic-associated diarrhea, Clostridium difficile infections, and irritable bowel syndrome (IBS). It supports digestive balance and restores gut flora during and after antibiotic use.

Comprehensive Product Description for Florastor
Generic Name: Saccharomyces boulardii lyo
Brand Name: Florastor
Other Names: SB Floractiv, Enterogermina (non-identical), BioSaccharomyces
Drug Class: Probiotic / Antidiarrheal / Gut Microflora Restorative Agent
Formulation: 250 mg oral capsules or sachets
Availability: Buy Florastor Online – EZ Chemist Pharmacy

Active Ingredient
Saccharomyces boulardii CNCM I-745
A unique, non-pathogenic, live yeast strain known for its gut flora-restoring and anti-toxin properties. This specific strain is clinically validated to survive gastric acid and colonize the GI tract temporarily, improving intestinal function and immunity.

Other Popular Names
S. boulardii probiotic

Yeast-based probiotic supplement

Saccharomyces boulardii lyo

Gut health capsules

Antibiotic-associated diarrhea prevention probiotic

Traveler’s diarrhea supplement

CNCM I-745 probiotic strain

Mode of Action
Saccharomyces boulardii CNCM I-745 works by:

Restoring Gut Microbiota – Replenishes beneficial gut flora during antibiotic use or gastrointestinal distress

Anti-toxin Binding – Binds and neutralizes bacterial toxins like Clostridium difficile toxin A and B

Immune Modulation – Stimulates secretory IgA and anti-inflammatory cytokines

Inhibiting Pathogen Adhesion – Prevents harmful bacteria from binding to intestinal walls

Enzyme Production – Produces enzymes such as proteases that degrade bacterial toxins

Clinically proven to reduce antibiotic-associated diarrhea by up to 60% in adults and children (McFarland LV et al., World Journal of Gastroenterology, 2010)

Indications / Uses
Florastor is used for:

Antibiotic-associated diarrhea (AAD)

Clostridium difficile infection (CDI) prevention and recurrence management

Traveler’s diarrhea

Acute infectious diarrhea in children and adults

Irritable Bowel Syndrome (IBS) – especially diarrhea-predominant (IBS-D)

Inflammatory Bowel Disease (IBD) – supportive adjunct

Post-antibiotic gut flora restoration

Pouchitis and post-surgical gut complications

Dosage & Administration
Age Group Recommended Dosage Frequency
Adults & Children >12 yrs 250 mg – 500 mg (1–2 capsules) 1–2 times daily
Children 6 months–12 yrs 250 mg (1 capsule or sachet) Once daily
Infants (under 6 months) Use only under medical supervision

With or without food

Can be opened and mixed with soft food or liquid (do not mix with hot liquids)

Take Florastor 2 hours apart from antifungal medications

Prescribing & Monitoring
Not a prescription medication in most countries, but recommended for physician-guided use alongside antibiotic therapies or in gut-related conditions.

May be continued for 7–10 days or throughout the course of antibiotics

Safety Information
Contraindications:
Patients with severely compromised immune systems (e.g., hematologic cancers, ICU patients)

Central venous catheter (risk of fungemia)

Allergic reaction to yeast or Saccharomyces species

Use with Caution:
Premature infants or severely immunocompromised patients

Do not use Florastor capsules if on antifungal agents like fluconazole or ketoconazole (decreases efficacy)

Pregnancy & Lactation:
Generally recognized as safe (GRAS) in pregnancy and breastfeeding

No adverse fetal effects noted in clinical literature

Side Effects
Common Side Effects:
Mild bloating or gas

Constipation (rare)

Increased thirst

Mild skin rash

Rare But Serious:
Fungemia (yeast in blood) – in immunocompromised or catheterized patients

Allergic reactions (rash, itching, swelling) – discontinue immediately

Drug Interactions
Antifungal drugs (e.g., fluconazole, itraconazole, ketoconazole) – Reduce effectiveness of S. boulardii

No significant interactions with antibiotics or other probiotics

Separate Florastor dose from oral antifungal medications by at least 8 hours

Drug Classification
Therapeutic Class: Probiotic supplement

Pharmacologic Class: Yeast-based microbiota modulator

Regulatory Class: OTC Dietary Supplement / Complementary Medicine (India, US, UK)

FDA Status: Recognized as safe for human consumption

Schedule: Non-scheduled (OTC)

Frequently Asked Questions (FAQs)
What is Florastor used for?
Florastor is used to prevent and treat diarrhea, especially antibiotic-associated diarrhea and Clostridium difficile infections. It also supports gut flora restoration and digestive health.

Is Florastor safe to take with antibiotics?
Yes, Florastor is clinically proven safe and effective with antibiotics. It should be taken at a different time of day from the antibiotic for best results.

Does Florastor contain dairy or gluten?
Florastor is gluten-free, dairy-free, and vegetarian-friendly.

How long can I take Florastor?
Florastor can be taken short-term (7–14 days) during antibiotics or longer-term for chronic conditions like IBS, under medical guidance.

Can children take Florastor?
Yes, Florastor is safe for children over 6 months old and available in sachets for easy dosing.

Is Florastor better than other probiotics?
Florastor uses a unique yeast strain (S. boulardii CNCM I-745) which is resistant to antibiotics and effective against bacterial toxins, giving it an advantage over traditional lactobacillus-based probiotics in antibiotic-associated conditions.