Vermox Syrup – Comprehensive Product Description
Brand Name: Vermox Syrup
Generic Name (Active Ingredient): Mebendazole
Other Popular/Generic Names: Antiworm Syrup, Mebendazole Suspension, Vermox Oral Suspension
Drug Classification: Anthelmintic / Anti-parasitic agent

What is Vermox Syrup used for?
Vermox Syrup contains mebendazole, an anthelmintic medication used to treat intestinal worm infections such as pinworm (Enterobius vermicularis), roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura), and hookworm (Ancylostoma duodenale, Necator americanus). It works by preventing the worms from absorbing glucose, leading to their death and elimination from the body. Suitable for both children and adults, Vermox Syrup is a clinically proven, first-line treatment for multiple helminth infections.

Product Overview
Vermox Syrup is a broad-spectrum anthelmintic suspension formulated for convenient administration, especially in children and patients with swallowing difficulties. It effectively targets common intestinal parasitic worms, improving gastrointestinal health, preventing reinfection, and reducing parasite-related complications.

Mode of Action (Pharmacodynamics)
Mechanism: Mebendazole binds to β-tubulin of parasitic worms, inhibiting microtubule formation.

This disrupts glucose uptake and other nutrient absorption processes in the parasite.

Without energy supply, the worm’s cellular structure collapses, leading to immobilization and death.

Dead worms are expelled naturally through bowel movements.

Onset of Action: Typically within 24–48 hours after the first dose.
Half-life: Approximately 3–6 hours (systemic absorption is minimal).

Clinical Uses (Indications)
Vermox Syrup is indicated for the treatment of:

Pinworm infection (Enterobiasis)

Roundworm infection (Ascariasis)

Whipworm infection (Trichuriasis)

Hookworm infection (Ancylostomiasis and Necatoriasis)

Mixed helminth infections (simultaneous multiple worm infestations)

Dosage & Administration
Formulation: Oral suspension (100 mg mebendazole per 5 ml)

Typical Dosage (as per WHO and clinical guidelines):

Pinworm:

Adults & children ≥2 years: Single 100 mg dose (5 ml syrup).

Repeat after 2 weeks if reinfection occurs.

Roundworm, Whipworm, Hookworm:

Adults & children ≥2 years: 100 mg twice daily (5 ml every 12 hours) for 3 consecutive days.

Children under 2 years: Not routinely recommended unless prescribed by a pediatrician.

Administration Tips:

Shake well before use.

Can be taken with or without food.

No special dietary restrictions required during treatment.

Prescribing Information
ATC Code: P02CA01

Absorption: Low systemic absorption; primarily acts locally in the gastrointestinal tract.

Metabolism: Liver (CYP450 enzymes).

Excretion: Biliary and renal pathways.

Safety Information
Side Effects (Generally Mild & Temporary)
Abdominal pain, bloating, diarrhea

Nausea, vomiting

Dizziness, headache

Rare: Hypersensitivity reactions (rash, urticaria, angioedema)

Warnings & Cautions
Not recommended in pregnancy (especially first trimester) unless benefits outweigh risks.

Use with caution in patients with liver disease.

Avoid in known hypersensitivity to mebendazole or excipients.

Maintain good hygiene (washing hands, trimming nails) to prevent reinfection.

Drug Interactions (Clinically Backed)
Metronidazole: Avoid combination—may increase risk of Stevens-Johnson syndrome.

Cimetidine: May increase plasma levels of mebendazole.

Carbamazepine & Phenytoin: May reduce mebendazole effectiveness via increased metabolism.
(Reference: WHO Model Formulary, Clinical Infectious Diseases Journal, 2020)

Storage Instructions
Store below 25°C in a dry place.

Keep bottle tightly closed.

Keep out of reach of children.

Frequently Asked Questions (FAQ)
Q1: Is Vermox Syrup safe for children?
Yes, Vermox Syrup is safe for children over 2 years when used in recommended doses. For children under 2 years, consult a pediatrician.

Q2: How long does Vermox Syrup take to work?
Most patients experience relief within 24–48 hours. Complete elimination of worms may take a few days.

Q3: Do I need a prescription for Vermox Syrup?
In most countries, mebendazole requires a prescription. Always follow a doctor’s guidance.

Q4: Can Vermox Syrup prevent worm infection?
No, Vermox treats existing infections but does not prevent reinfection. Maintaining hygiene is essential.

Q5: Can pregnant women take Vermox Syrup?
Not recommended during the first trimester. Later use should be considered only if medically necessary.