Myfortic – Buy Myfortic Delayed-Release Tablets Online at EZ Chemist Pharmacy

Myfortic (mycophenolic acid) is an immunosuppressant medication used to prevent organ rejection in kidney transplant patients. It works by inhibiting inosine monophosphate dehydrogenase (IMPDH), thereby reducing the proliferation of T- and B-lymphocytes. Myfortic is used in combination with cyclosporine and corticosteroids.

Product Name:
Myfortic

Generic Name:
Mycophenolic Acid (MPA)

Other Common Names:
Myfortic Delayed-Release Tablets

Mycophenolate Sodium

Enteric-Coated Mycophenolate

MPA (active metabolite of Mycophenolate Mofetil)

Drug Classification:
Therapeutic Class: Immunosuppressant

Pharmacologic Class: Selective Inhibitor of Inosine Monophosphate Dehydrogenase (IMPDH)

Active Ingredient:
Mycophenolic acid (as Mycophenolate sodium)

Mechanism of Action:
Myfortic inhibits the enzyme inosine monophosphate dehydrogenase (IMPDH), which is critical for de novo synthesis of guanosine nucleotides. This mechanism suppresses the proliferation of T and B lymphocytes, which rely on this pathway, thus reducing immune response and preventing organ rejection post-transplantation.

Uses and Indications:
Indicated for:

Prevention of acute renal allograft rejection in adult kidney transplant recipients

Used in combination with cyclosporine (non-modified) and corticosteroids

Off-label use may include:

Refractory autoimmune diseases (e.g., lupus nephritis, psoriasis) under specialist supervision

Dosage and Administration:
Standard Adult Dose: 720 mg orally twice daily (total 1440 mg/day)

Administer on an empty stomach (1 hour before or 2 hours after food)

Do not crush, chew, or split the delayed-release tablets

Renal Impairment:

No dosage adjustment required in mild/moderate renal dysfunction

Avoid in severe renal impairment unless benefits outweigh risks

Prescribing Information:
Available strengths: 180 mg, 360 mg delayed-release tablets

Not interchangeable with CellCept (mycophenolate mofetil) on a mg-to-mg basis

Ensure therapeutic drug monitoring in high-risk patients (e.g., high rejection risk, drug interactions)

Safety Information:
Pregnancy Category D: Causes fetal harm. Use only with strict contraception and REMS (Risk Evaluation and Mitigation Strategy) adherence

Use in lactation is not recommended

Monitor complete blood count (CBC) and renal function regularly

Side Effects:
Common side effects:

Diarrhea

Vomiting

Abdominal pain

Leukopenia

Headache

Increased risk of infections (UTIs, respiratory infections)

Serious side effects:

Progressive multifocal leukoencephalopathy (PML)

Cytopenias (anemia, neutropenia)

Lymphoma and skin malignancy with long-term use

GI tract perforations (rare)

Warnings and Precautions:
Pregnancy Warning: Teratogenic. Two forms of contraception recommended before, during, and for 6 weeks after therapy

Bone marrow suppression risk: Monitor CBC frequently

Live vaccines are contraindicated during treatment

Increased risk of lymphoma and skin cancer: Minimize sunlight exposure

Not recommended in liver transplant recipients

Drug Interactions:
Antacids and proton pump inhibitors (PPIs): May reduce absorption

Acyclovir/ganciclovir: Additive nephrotoxicity

Rifampin, cholestyramine: Decrease MPA exposure

Cyclosporine: Alters enterohepatic recirculation of MPA

Live vaccines (e.g., MMR, varicella): Contraindicated

Storage Instructions:
Store at room temperature (15°C to 30°C)

Protect from moisture and heat

Keep out of reach of children

FAQs for Myfortic – EZ Chemist Online Pharmacy
Q1. What is Myfortic used for?
Myfortic is used to prevent kidney transplant rejection by suppressing the immune system. It is always used with cyclosporine and steroids.

Q2. Is Myfortic the same as CellCept?
No. Although both convert to mycophenolic acid, Myfortic is an enteric-coated form, and they are not interchangeable on a milligram-to-milligram basis.

Q3. Can Myfortic be used during pregnancy?
No. Myfortic is highly teratogenic and should only be used under strict conditions with effective birth control.

Q4. What are the common side effects of Myfortic?
Diarrhea, leukopenia, vomiting, and increased infection risk are common.

Q5. Can I take antacids with Myfortic?
Avoid antacids within 2 hours of Myfortic as they may reduce drug absorption.

Q6. Where can I buy Myfortic online?
You can securely buy Myfortic 180 mg or 360 mg online from EZ Chemist Pharmacy, with prescription validation and shipping support.