Product Name: Diclectin Tablets – Safe Morning Sickness Relief During Pregnancy – Buy Online at EZ Chemist Pharmacy

Diclectin is a prescription medication combining doxylamine and pyridoxine (vitamin B6), clinically approved for treating nausea and vomiting during pregnancy. It is considered safe and effective when used as directed by a physician. Buy Diclectin online at EZ Chemist Pharmacy.

Comprehensive Product Description: Diclectin
Generic Name: Doxylamine Succinate + Pyridoxine Hydrochloride
Brand Names: Diclectin, Diclegis (US), Xonvea (UK)
Drug Class: Antiemetic / Antihistamine-Vitamin Combination
Dosage Form: Extended-release tablets
Strength: 10 mg doxylamine + 10 mg pyridoxine per tablet
Availability: Buy Diclectin Online – EZ Chemist Pharmacy

Active Ingredients
Doxylamine Succinate (10 mg): A first-generation antihistamine that reduces nausea by acting on histaminergic receptors in the brain.

Pyridoxine Hydrochloride (10 mg): A form of vitamin B6 that aids in neurotransmitter regulation and reduces nausea symptoms in pregnancy.

Other Common and Popular Names
Diclegis (US)

Xonvea (UK)

Doxylamine-Pyridoxine combo

Vitamin B6 and antihistamine for pregnancy nausea

Pregnancy-safe nausea relief

Mode of Action
Doxylamine acts as a histamine H1-receptor antagonist, suppressing the vomiting center in the brain and reducing vestibular stimulation.
Pyridoxine modulates neurotransmitter levels involved in nausea regulation. Together, they offer a synergistic antiemetic effect for treating nausea and vomiting of pregnancy (NVP).

Uses of Diclectin
Treatment of morning sickness in pregnant women

First-line therapy for nausea and vomiting during pregnancy (NVP)

Clinically validated for safe use from the first trimester onward

Off-label Uses:
Rarely used outside pregnancy-associated nausea due to its targeted design.

Dosage and Administration
Recommended Initial Dose:

2 tablets at bedtime on Day 1.

Titration Based on Symptoms:

If symptoms persist, 1 tablet in the morning and 2 at bedtime on Day 2.

If still symptomatic, 1 tablet in the morning, 1 in the afternoon, and 2 at bedtime (maximum: 4 tablets/day).

Route: Oral (Swallowed whole; do not crush or chew)
Onset of Action: Delayed due to extended-release formulation (start treatment proactively)

Prescribing Information
Start with bedtime dose and titrate based on severity

Administer consistently for effectiveness

Do not exceed 4 tablets in 24 hours

Use only under the supervision of a healthcare provider, especially during the first trimester

May take 4–6 days to observe full benefit

Safety Information
Approved for pregnancy by Health Canada and FDA under Pregnancy Category A (Diclegis)

Considered safe in all trimesters based on multiple cohort studies and meta-analyses

Does not increase fetal malformation risk

Use Cautiously In:

Women with asthma, glaucoma, or urinary retention

Sedative-sensitive individuals

Breastfeeding:

Use with caution; doxylamine may pass into breastmilk and cause infant drowsiness or irritability

Side Effects of Diclectin
Common Side Effects:

Drowsiness or sedation

Dry mouth

Dizziness

Fatigue

Constipation

Less Common (Rare):

Blurred vision

Confusion (in high doses or sensitive individuals)

Allergic rash

Warnings and Cautions
May cause drowsiness; avoid driving or operating machinery

Avoid concurrent use with alcohol, CNS depressants, or sedatives

Not recommended for women with hypersensitivity to antihistamines or pyridoxine

Not indicated for hyperemesis gravidarum (severe vomiting requiring hospitalization)

Drug Interactions
Known Interactions:

CNS depressants (e.g., benzodiazepines, opioids): Enhanced sedative effect

MAO inhibitors (e.g., isocarboxazid): May intensify anticholinergic side effects

Alcohol: Potentiates drowsiness and cognitive slowing

Other vitamin supplements: Monitor for excessive pyridoxine intake

Clinical Note:
A large cohort study by Einarson et al., 2010 confirmed no increased teratogenicity or miscarriage risk with doxylamine-pyridoxine (PMID: 20641163).

Drug Classification
ATC Code: A04AD12

Legal Status: Prescription Only (Rx)

Pregnancy Classification: FDA Category A (Diclegis)

Frequently Asked Questions (FAQs)
What is Diclectin used for?
Diclectin is prescribed for managing nausea and vomiting during pregnancy (morning sickness). It is the first-line treatment recommended by obstetric guidelines.

Is Diclectin safe in pregnancy?
Yes. Diclectin has been extensively studied and is considered safe throughout all trimesters of pregnancy. It does not increase the risk of birth defects.

How long can I take Diclectin?
It can be used throughout pregnancy under medical supervision. Treatment duration depends on symptom severity and clinical response.

Can I take Diclectin with other medications?
Avoid alcohol and other sedatives while taking Diclectin. Always consult your doctor before combining medications during pregnancy.